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Elizabeth J. Harbron

Department of Chemistry
William & Mary
P.O. Box 8795
Williamsburg, VA 23187
phone: (757)221-2557

2017 - present Floyd D. Gottwald, Sr. Professor of Chemistry, W&M
2017 - present Associate Chair of Chemistry, W&M
2016 - present  Professor of Chemistry, W&M
2008 – 2016  Associate Professor of Chemistry, W&M
2002 – 2008  Assistant Professor of Chemistry, College of William and Mary
1999 – 2002  NIH Postdoctoral Research Fellow
         Dept. of Chemistry and Biochemistry, Univ. of Texas at Austin
         Research Advisor: Prof. Paul F. Barbara

Aug. 1999     Ph.D. in Organic Chemistry, Univ. of North Carolina at Chapel Hill
                     Dissertation: “Electron Paramagnetic Resonance Studies of Molecular
                     Motions in Polymers”
                     Research Advisor: Prof. Malcolm D.E. Forbes

May 1995     B.A. in Chemistry and Gender and Women’s Studies, Grinnell College
                     Research Advisor: Prof. James E. Swartz

2015-2017       English-Stonehouse Faculty Fellow, College of William and Mary
2013                Arts & Sciences Award for Teaching Excellence
2013                Plumeri Award for Faculty Excellence         
2011-2014       University Professor for Teaching Excellence
2011                Thomas Jefferson Teaching Award
2008                College of William and Mary Alumni Fellowship Award (for teaching)
2008                Inter-American Photochemical Society Young Investigator Award
2000-2002       National Institutes of Health NRSA Postdoctoral Fellowship
1996-1999       National Science Foundation Predoctoral Fellowship
1999                Richard D. Gilbert Award in Polymer Science, given by American Chemical Society North Carolina Section Polymer Discussion Group
1995-1996       Charles N. Reilley Memorial Fellowship, University of North Carolina
1995-1996       Frances Preston Venable Chemistry Scholarship, UNC
1995                graduation with honors, Grinnell College
1994                Phi Beta Kappa
1991-1995       Trustee Honor Scholarship, Grinnell College

Funded External Grants

National Science Foundation, "Controlled Amplification of Photochemical Reactions in Conjugated Polymer Nanoparticles," 2019-2022, $340,000.

National Science Foundation, "Harnessing Amplified Fluorescence Resonance Energy Transfer in Conjugated Polymer Nanoparticles," 2015-2018 with extension to 2020, $319,000.

Henry Dreyfus Teacher-Scholar Award, “New Stimulus-Responsive Fluorescent Systems: Rhodamine Spirolactam Sensors for Mercury and pH,” 2010-2015, $60,000.

National Science Foundation CAREER, “Toward Photocontrol of Conjugated Polymer Emission: Modulation of Fluorescence Properties in Photochromic Poly(p-phenylenevinylene) Derivatives,” 2007-2012, $404,000.

Jeffress Memorial Trust, “Factors Influencing the Kinetics of Aromatic Stacking in an Azobenzene Photoswitch,” 2003-2004 with extension to 6/2005, $25,000.

Camille and Henry Dreyfus New Faculty Start-up Grant for Undergraduate Institutions, “Probing the Specificity of Protein/DNA Interactions with Ensemble and Single Molecule Spectroscopy,” 2002-2007, $20,000.

Independent career refereed publications, William & Mary undergraduates in bold, masters students italicized

Graves, L.S.; Goodwin, M.J.; Maricar, I.N.; Rebstock, J.A.; Harbron, E.J. "Maximizing Amplified Energy Transfer: Tuning Particle Size and Dye Loading in Conjugated Polymer Nanoparticles," J. Phys. Chem. C 2020, 124, 26474-26485.

Zhang, X.; Kurimoto, A.; Frank, N.L.; Harbron, E.J. "Controlling Photoswitching via pcFRET in Conjugated Polymer Nanoparticles," J. Phys. Chem. C, 2018 122, 22728-22737. Selected as ACS Editors' Choice article.

Stratton, S.G.; Taumoefolau, G.H.; Purnell, G.E.; Rasooly, M.; Czaplyski, W.L.; Harbron, E.J. "Tuning the pKa of Fluorescent Rhodamine pH Probes via Substituent Effects," Chem. Eur. J. 2017, 23, 14064-14072.

Villa, J.K.; Tran, H.-A.; Vipani, M.; Gianturco, S.; Bhasin, K.; Russell, B.L.; Harbron, E.J.; Young, D.D. "Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids," Molecules 2017, 22, 1194.

Zhang, X.; Chamberlayne, C.F.; Kurimoto, A.; Frank, N.L.; Harbron, E.J. "Visible Light Photoswitching of Conjugated Polymer Nanoparticle Fluorescence," Chem. Comm. 2016, 52, 4144-4147.

Chamberlayne, C.F.; Lepekhina, E.A.; Saar, B.D.; Peth, K.A.; Walk, J.T.; Harbron, E.J. “Functionalization of Conjugated Polymer Nanoparticles for Fluorescence Photomodulation,” Langmuir 2014, 30, 14658-14669.

Czaplyski, W.L.; Purnell, G.E.; Roberts, C.A.; Allred, R.M.; Harbron, E.J.  “Substituent Effects on the Turn-on Kinetics of Rhodamine-based Fluorescent pH Probes,”  Org. Biomol. Chem. 2014, 12, 526-533.

Harbron, E.J. “Fluorescence Intensity Modulation in Photochromic Conjugated Polymer Systems,” Isr. J. Chem. 2013, 53, 256-266.  Invited paper for special issue “Photochromic Control of Molecular and Macroscopic Properties.”

Childress, E.S.; Roberts, C.A.; Sherwood, D.Y.; LeGuyader, C.L.M.; Harbron, E.J. “Ratiometric Fluorescence Detection of Mercury Ions in Water by Conjugated Polymer Nanoparticles,” Anal. Chem. 2012, 84, 1235-1239.

Davis, C.M.; Childress, E.S.; Harbron, E.J.  “Ensemble and Single Particle Fluorescence Photomodulation in Diarylethene-Doped Conjugated Polymer Nanoparticles,” J. Phys. Chem. C 2011, 115, 19065–19073.

Harbron, E.J. “Photochromic Nanoparticles,” Photochemistry 2011, 39, 211-227.

Harbron, E.J.; Davis, C.M.; Campbell, J.K.; Allred, R.M.; Kovary, M.T.; Economou, N.J. “Photochromic Dye-Doped Conjugated Polymer Nanoparticles: Photomodulated Emission and Nanoenvironmental Characterization,” J. Phys. Chem. C 2009, 113, 13707-13714.

Grimes, A.F.; Call, S.E.; Harbron, E.J.; English, D.S. “Wavelength-Resolved Studies of Förster Energy Transfer in Azobenzene-Modified Conjugated Polymers: The Competing Roles of Exciton Migration and Spectral Resonance,” J. Phys. Chem. C, 2007, 111, 14257-14265.

Lewis, S.M.; Harbron, E.J. “Photomodulated PPV Emission in an Photochromic Polymer Film,” J. Phys. Chem. C 2007, 111, 4425-4430.

Harbron, E.J.; Hadley, D.H.; Imm, M.R. “Solvent Effects on Phototriggered Conformational Changes in an Azobenzene-Functionalized Poly(p-phenylene vinylene),” J. Photochem. Photobiol. A: Chem. 2007, 186, 151-157.

Grimes, A.F.; Call, S.E.; Vicente, D.A.; English, D.S.; Harbron, E.J. “Toward Efficient Photomodulation of Conjugated Polymer Emission: Optimizing Differential Energy Transfer in Azobenzene-Substituted PPV Derivatives,” J. Phys. Chem. B 2006, 110, 19183-19190.

Harbron, E.J.; Vicente, D.A.; Hadley, D.H.; Imm, M.R.  “Phototriggered Fluorescence Color Changes in Azobenzene-Functionalized Conjugated Polymers,” J. Phys. Chem. A, 2005, 109, 10846-10853. 

Harbron, E.J.; Vicente, D.A.; Hoyt, M.T. “Fluorescence Modulation via Isomer-Dependent Energy Transfer in an Azobenzene-Functionalized PPV Derivative,” J. Phys. Chem. B 2004, 108, 18789-18792.